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    "titulo" => "El sildenafil afecta el rendiment físic en altitud? Evidències científiques actuals"
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        "resumen" => "<p class="elsevierStylePara"> El sildenafil ha demostrat efic&#224;cia en reduir la hipertensi&#243; pulmonar provocada per la vasoconstricci&#243; pulmonar hip&#242;xica&#46; El seu paper com a possible factor per augmentar el rendiment de l&#8217;exercici en condicions d&#8217;hip&#242;xia est&#224; per demostrar&#44; per&#242; l&#8217;&#250;s del sildenafil ha augmentat entre els muntanyencs&#44; no com a f&#224;rmac preventiu de l&#8217;edema pulmonar de gran altitud&#44; sin&#243; perqu&#232; es pensava que podria ajudar a millorar el rendiment f&#237;sic a gran altitud&#46; Diversos estudis han plantejat el tema&#44; amb resultats contradictoris&#46; Actualment&#44; tot i que no hi ha dades concloents&#44; ni en altitud simulada ni real&#44; i amb l&#8217;evid&#232;ncia clara que en norm&#242;xia el sildenafil no millora el rendiment f&#237;sic&#44; es continua utilitzant aquesta subst&#224;ncia &#40;a vegades en exc&#233;s&#41; per persones que pugen els alts cims&#46; Aquesta hipot&#232;tica millora del rendiment dep&#232;n del grau d&#8217;hipox&#232;mia en altitud i de la capacitat de resposta individual a aquest medicament&#46; Aquest article revisa el coneixement actual sobre aquest tema&#46;</p>"
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        "resumen" => "<p class="elsevierStylePara"> Sildenafil has proven to efficiently reduce the increase in pulmonary artery pressure provoked by hypoxic pulmonary vasoconstriction&#46; However&#44; its role as a possible factor in increasing exercise performance under hypoxic conditions remains to be demonstrated&#46; The use of sildenafil has increased among mountaineers&#44; not as a high altitude pulmonary edema preventive drug&#44; but as a means that could help to improve performance&#46; Several studies have attempted to address this issue&#44; with conflicting results&#46; Currently&#44; despite the inconclusive data at simulated or real altitude&#44; and with the clear evidence that&#44; in normoxia&#44; sildenafil does not improve performance&#44; this drug is being used &#40;and sometimes overused&#41; by people who climb high peaks&#46; However&#44; such potential performance improvement would depend on the degree of hypoxemia &#40;altitude&#41; and the individual responsiveness to this drug&#46; This paper reviews the current knowledge on this matter&#46;</p>"
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