The sports activity requires of the harmonic and fine movement, and development and maturity of central nervous system and muscle-skeletal system is very important. Children with Down syndrome seen to love sports and can be very competitive, the performance were influenced for the neurological damage and reflect in the muscular activity. In the Down syndrome occur because the chromosomal abnormality results in a defect in production of normal collagen in the generalize laxity ligamentous and decrease muscle tone. Thirty men athletes was participated in V National Game, 2006 in weightlifting with different causes for discapacity (genetic, 7; environmental, 4; multifactors, 3; unknown, 9; perinatal, 7) were select for determinate the relation among anthropologic measure (weight, age), and degree of discapacity and sportive result. Data are presented as mean ± SD. The significance of differences was evaluated by Mann-Whitney test. P <0,05 was considered significant. In this study we found that Down syndrome athletes present lowest sportive result that the others intellectual discapacity with same degree for discapacity. Not found relation between anthropologic measure and performance.