The use of hypoxia in professional football training is not widely used although improvements in physical performance obtained with hypoxia could be relevant for the fitness and physical recovery. Football is defined as an intermittent effort sport and requires that players recover as quickly as possible between great efforts. In a study previously carried out by this research group a significant improvement was found in heart rate recovery from maximal exercise after performing strength resistance training in intermittent hypoxia. Similarly, the physiological benefits of exposure and training in hypoxia may increase the individual performance of soccer players. The main aim of this review is analyze the literature on the use and possible applications of hypoxia training for physical performance in football.