Background: To evaluate changes in the quality of life (QoL),of asthmatic children after aqua aerobic exercise in an air-conditioned environment. Subjects and methods: We divided 22 asthmatic children into two groups: an experimental group and a control group, with 11 children in each group. Each child was administered the specially designed quality of life questionnaire for asthmatic children (PAQLQ). The experimental group was also given aqua aerobic training in an air-conditioned environment, lasting 18 weeks, after which the PAQLQ was repeated in both groups. Results: The initial results of the PAQLQ questionnaire showed that in 8 of the 23 questions the experimental group had lower average QoL values ( P=.05). When comparing the sum of the differences in the results at the second application minus the initial results in both groups, we found a significant improvement in the QoL of the experimental group compared with that in the control group (experimental group: 582; control group: ­32). Conclusion: Aqua-aerobic exercise in an air-conditioned environment improves the QoL of asthmatic children and can be considered a prophylactic factor in the prevention of exercise-induced crises.