Publish in this journal
Journal Information
Vol. 54. Issue 203.
Pages 91-101 (July - September 2019)
Share
Share
Download PDF
More article options
ePub
Visits
...
Vol. 54. Issue 203.
Pages 91-101 (July - September 2019)
Original Article
Salivary levels of Interleukin-6 and Tumor Necrosis Factor-alpha in girls aged 7–17 years practicing volleyball
Niveles salivales de interleucina 6 y factor de necrosis tumoral alfa en niñas de 7 a 17 años que practican voleibol
Visits
...
Carolina da Silva Peresa, Roberta Pratti Gavaa, Igor Renan Zena, Julio Cesar Molina Correab, Gabriela Fleury Seixasc, Carla Cristiane Silvad,
Corresponding author
ccsilva@uenp.edu.br

Corresponding author.
, Cassia Cilene Dezan Garbelinie, Solange de Paula Ramosf
a Master in Dentistry, Health Sciences Center, State University of Londrina, Rodovia Celso Garcia Cid, PR 445 km380, Londrina, PR, Brazil
b Master in Physical Education, Center of Physical Education and Sports, State University of Londrina, Rodovia Celso Garcia Cid, PR 445 km380, Londrina, PR, Brazil
c Faculty of Odontology, Universidade Norte do Paraná, Rua Marselha, 60, Londrina, PR, Brazil
d Department of Physical Education, State University of the North of Paraná, Alameda Padre Magno, 841, Jacarezinho, Londrina, PR, Brazil
e Department of Oral Medicine and Pediatrics Dentistry, Health Sciences Center, State University of Londrina, Rodovia Celso Garcia Cid, PR 445 km380, Londrina, PR, Brazil
f Department of Histology, Center of Biologial Sciences, State University of Londrina, Rodovia Celso Garcia Cid, PR 445 km380, Londrina, PR, Brazil
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Tables (3)
Table 1. Characteristics of participants involved in volleyball practice (n=120).
Table 2. Multivariate linear regression analysis of salivary IL-6 concentration and study variables (n=120).
Table 3. Multivariate linear regression analysis of salivary TNFα concentration and study variables.
Show moreShow less
Abstract
Introduction

The purpose of the study was to evaluate the salivary concentrations of Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNFα) and correlate the findings with the caries index, body mass index (BMI), potency of lower limbs (vertical jump), cardiorespiratory fitness, and risk of developing cardiovascular diseases in girls practicing volleyball.

Material and methods

Two studies were performed: 1) a cross-sectional study (n=120) on the association of IL-6 and TNFα with the caries index, anthropometric measures, physical tests, and experience in volleyball practice; 2) longitudinal study (n=63) on the effects of 8 weeks of training on salivary IL-6 and TNFα in girls with intermediate experience in volleyball and competitive girls.

Results

The median levels of IL-6 were 1.98 [1.55–3.11]pg/ml and TNFα, 0.46 [0.28–0.59]pg/ml and these did not correlate with the caries index, BMI, training volume, training practice, or cardiovascular risk. A correlation was observed between IL-6 and TNFα (r=0.34; p<0.001), IL-6 and vertical jump height (r=−0.28, p<0.005), and TNFα and age (r=0.33; p<0.001). After 8 weeks of training, TNFα levels increased in the intermediate and competitive groups (p<0.05), while IL-6 levels decreased only in the intermediate level group (p<0.05).

Conclusion

the median levels of IL-6 and TNFα did not correlate with the caries index, BMI, training volume, experience practice, or cardiovascular risk. Salivary levels of IL-6 were downmodulated in the group with intermediate experience and TNFα was upmodulated by training.

Keywords:
Saliva
Cytokines
Youth sports
Adolescents
Volleyball
Resumen
Introducción

el objetivo del estudio fue evaluar las concentraciones salivales de interleukina-6 (IL-6) y factor de necrosis tumoral alfa (TNFα) y correlacionarlas con el índice de caries, el índice de masa corporal (IMC), potencia muscular de miembros inferiores (salto vertical), la aptitud cardiorrespiratoria y riesgo de desarrollar enfermedades cardiovasculares en niñas que practican voleibol.

Material y métodos

se realizaron dos estudios: 1) un estudio transversal (n = 120) sobre la asociación de IL-6 y TNFα con índice de caries, medidas antropométricas, pruebas físicas y experiencia en la práctica de voleibol; 2) estudio longitudinal (n = 63) sobre el efecto de 8 semanas de entrenamiento em IL-6 y TNFα salivales en niñas con experiencia intermedia en voleibol y chicas competitivas.

Resultados

los niveles medianos de IL-6 fueron 1.98 [1.55 - 3.11] pg/ml y TNFα fue 0.46 [0.28 - 0.59] pg/ml y no se correlacionaron con el índice de caries, el IMC, el volumen de entrenamiento, la práctica de entrenamiento y el riesgo cardiovascular. Se observó una correlación entre IL-6 y TNFα (r = 0.34; p <0.001), IL-6 y altura de salto vertical (r = -0.28, p <0.005), y TNFα y edad (r = 0.33; p < 0.001). Después de 8 semanas de entrenamiento, los niveles de TNFα aumentaron en los grupos intermedios y competitivos (p <0.05), mientras que los niveles de IL-6 disminuyeron solo en el grupo intermedio (p <0.05).

Conclusión

los niveles medianos de IL-6 y TNFα no se correlacionaron con el índice de caries, el IMC, el volumen de entrenamiento, la experiencia práctica y el riesgo cardiovascular. Los niveles salivales de IL-6 se modificaron a la baja en el grupo con experiencia intermedia y el TNFα se moduló al alza mediante el entrenamiento.

Palabras clave:
Saliva
Citoquinas
Deporte juvenil
Adolescentes
Voleibol

Article

These are the options to access the full texts of the publication Apunts Sports Medicine
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Apunts Sports Medicine

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Apunts Sports Medicine

Subscribe to our newsletter

Article options
Tools

Are you a health professional able to prescribe or dispense drugs?